Do you want your laspest grow strong and healthy person? Then take care that he did not grow up in Extra ordinary clean and sterile environment. U.S. scientists have finally officially confirmed that early childhood exposure to all kinds of microbes significantly affects the sensitivity of all sorts of allergies and autoimmune diseases in adult life.Let then these are the hay fever, asthma or inflammatory bowel disease is mediated by Physorg.com .
Previously considered to be the hygiene hypothesis, which explains why the world is in today’s urban areas has significantly increased the incidence of allergies and autoimmune diseases. According to this but so far there was no scientific confirmation.
Now, however, is found in the hypothesis statement and explained the possible mechanism of this evokes.
Experiment, researchers used the so-called sterile mice. Their immune system was studied and compared with results in normal circumstances, a variety of bacteria grown with that of mice. Showed that the bacteria-free mice were more adults, pneumonia, intestinal inflammation and astamt. This all results in cell-mediated immunity involved in T-cell hyperactivity. This phenomenon is associated with the above-mentioned diseases in both mice and humans.
The test also showed that, when placed in bacteria-free mice during the first week of life microbial environment, their immune systems returned to normal and subsequently managed to avoid these diseases. If it was, however, adult mice, it did not show the same result.
The researchers say this is an example of the importance of the immune system to microbial adaptation to the very earliest period of life. According to them, it is possible to proceed to further studies in the course of specific microbial factors that are responsible for the protection of allergic reactions and autoimmune diseases, anti-metabolites. In doing so teadlsed emphasize that the mechanism identified in mice, further work needs to be sure to include testing on humans.
This study was published in the journal Science ‘s website.