The obsessive compulsive disorder (OCD) is an anxiety disorder characterized by intrusive, recurrent and persistent thoughts that produce uneasiness, apprehension, fear or concern. Also, with the aim of reducing this anxiety, repetitive behaviors occur.
Despite the various symptoms of the disease, new research suggests that obsessive compulsive disorder may be mediated by a single brain receptor , thus providing a clear target for new drugs and treatments for this disorder.
So a team of researchers led by neuroscientists at Duke University have described how mice that have been bred to lack a gene called SAPAP3 (which plays a key role in the formation of synapses between brain cells) developed a tendency groom themselves excessively, as they have been published in the journal Biological Psychiatry .
This led them to speculate that the same gene may be largely responsible for obsessive compulsive disorder in humans. Based on this discovery, the researchers injected into mice a chemical that disables mGluR5 receptors, and then incredibly his TOC disappeared in a few minutes .
The finding gives us important clues about a possible mechanism for obsessive compulsive disorder, a debilitating psychiatric condition affecting up to 2 percent of the world population, and is now allowing further studies in human subjects to verify that the same thing happens in mice .
More About Obsessive Compulsive Disorder
Obsessive compulsive disorder may be a severe and disabling clinical condition that sometimes arises in late adolescence or early adulthood and, if left untreated, incorporates a chronic course. whether or not this disorder ought to be classified as associate degree folie or during a cluster of supposed obsessive compulsive related disorders continues to be a matter of dialogue. Biological models of psychoneurotic disorder propose anomalies within the 5-hydroxytryptamine pathway and dysfunctional circuits within the orbito-striatal space and dorsolateral anterior cortex. Support for these models is mixed and that they don’t account for the symptomatic heterogeneousness of the disorder. The cognitive-behavioural model of psychoneurotic disorder, that has some empirical support however doesn’t absolutely justify the disorder, emphasises the importance of dysfunctional beliefs in people affected. each biological and psychological feature models have light-emitting diode to empirical treatments for the disorder—ie, serotonin-reuptake inhibitors and varied kinds of cognitive-behavioural medical care. New developments within the treatment of psychoneurotic disorder involve medications that job in conjunction with cognitive-behavioural medical care, the foremost promising of that is D-cycloserine.
We hope that our article will help you to understand Obsessive compulsive disorder and its effects.
Via | IFLScience
Image | MIKI Yoshihito. (#mikiyoshihito)