The obsessive-compulsive disorder (OCD) is an anxiety disorder characterized by intrusive, recurrent and persistent thoughts that produce uneasiness, apprehension, fear or concern. Also, with the aim of reducing this anxiety, repetitive behaviors occur.
Despite the various symptoms of the disease, new research suggests that OCD may be mediated by a single brain receptor , thus providing a clear target for new drugs and treatments for this disorder.
So a team of researchers led by neuro scientists at Duke University have described how mice that have been bred to lack a gene called SAPAP3 (which plays a key role in the formation of synapses between brain cells) developed a tendency groom themselves excessively, as they have been published in the journal Biological Psychiatry .
This led them to speculate that the same gene may be largely responsible for OCD in humans. Based on this discovery, the researchers injected into mice a chemical that disables mGluR5 receptors, and then incredibly his TOC disappeared in a few minutes .
The finding gives us important clues about a possible mechanism for OCD, a debilitating psychiatric condition affecting up to 2 percent of the world population, and is now allowing further studies in human subjects to verify that the same thing happens in mice .
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